Platinuming Blasphemous 2 is not impossible, and it’s generally achievable in a single run.
If you don’t want to achieve the platinum but unlock both endings, you can do it in the first run, as once you defeat the final boss and watch the credits, you can resume the game and fight the final boss again, namely Incarnated Incarnate Devotion.
Here is the list of trophies, including the secret ones.
Platinum Trophy
The Penitent Two: Complete all Trophies
Gold Trophies
Second Psalm: Unlock Ending B
(That is, the ending you obtain by completing the game without necessarily finishing all the side quests)
Canvas of Light and Time: Unlock Ending A
(More precisely, to obtain ending A, there are the following requirements to fulfill: find the four golden figures, which are the statues to be placed in the Altar Blades: Cierzo, Lebeche, Gregal, Jaloque. Once all four of them are obtained and you have access to the room adjacent to the Chapel of the Five Doves, where you’ll find a brazier, you’ll need to arrange them in a specific order: Cierzo on top left inside; Gregal on top right inside; Lebeche on bottom left inside; Jaloque on bottom right inside. When arranged in this way, once you reach the brazier, they will burn, and you will obtain the Incense of the Envoys. At the moment of Ascension, to confront the Incarnate Devotion, you will have to choose whether to donate the Incense. If you choose to donate it, you will unlock ending A)
Silver Trophies
The Wait is Over: Defeat Eviterno, Father of Penitents
Flawless Penance: After the first fight, defeat any boss without receiving damage
A Sharp Rendezvous: Reach the room of the Sentinel of the Emery in under 30 minutes
A Thousand Years Later: Defeat the Faceless One, Chisel of Oblivion
A Heart of Gold: Defeat the Devotion Incarnate, the last child of the Miracle
True Martyrdom: Complete 100% of the game
Fermosa Fembra: Defeat Svsona, Fermosa Fembra
The Sea dies on the Shore: Defeat Odón of the Confraternity of Salt
The Last Ascension: Defeat Benedicta of the Confraternity of Endless Orison
The Sharpest Tool in the Shed: Defeat the Sentinel of the Emery
Forged in Fire: Defeat Sínodo, Hymn of a Thousand Voices
Blood and Gold: Defeat Orospina of the Confraternity of Embroiderers
Blood and Dust: Defeat the Great Preceptor Radamés
Blood and Iron: Defeat Lesmes of the Confraternity of Incorruptible Flesh
Bronze Trophies
Storm of Death: Unlock the true power of Sarmiento & Centella
Acta, Non Verba: Find all of the Prayers
Ultima ratio: Unlock all Abilities
Blessed Incense: Unlock the true power of Veredicto
Warrior of the Silent Sorrow: Unlock all Weapon Memories
Edge of Orison: Unlock the true power of Ruego Al Alba
The Merciless One:Execute 50 different enemies
Welcome Back!: Fall into spikes and survive
Happy New Year!: Toll a bell 12 times
Two Old Ones Eating Soup: Reunite Cástula with Trifón
(Once you’ve completed the quest of the two elders in the Palace of Embroideries and obtained the figures, namely the statues for the Altar Blade, Cástula and Trifón, it will be sufficient to pair them)
The Finest Craftmanship: Unlock all slots in the Altarpiece of Favours
This Is Blasphemy: Deal more than 250 damage with a single strike
Nobody Expects the Spanish Inquisition!: Kill every type of enemy
Twisted is the Path of the Miracle: Hear the echoes of the past
(There is a tree at Mother of Mothers, near which you will need to pause and listen to all the voices)
The Anointed One: Kill 300 enemies using Veredicto
The Veteran One: Kill 300 enemies using Sarmiento & Centella
The Punished One: Kill 300 enemies using Ruego Al Alba
A Leap of Faith: Lift the Curse of the Unforgiven
House of Grief and Hatred: Complete all the battle challenges
The Work of a Master: Bring every Remembrance to an artisan and turn them into Figures
Empty Handed: Purchase all available items in the shop in the City of the Blessed Name
No Cherub Left Behind: Free Próximo’s brothers
Still Among Us: Find all of the hidden symbols
Soledad: Unlock all of the Rosary Bead slots
Acquired Taste: Unlock all Bile Flasks
Second Pilgrimage: Reveal the whole map
Weight of Penance: Find all of the Figures
Full Devotion: Find all of the Rosary Beads
Hide and Seek: Find all the hidden Cobijadas
If you want to read more, here is our Review.